An Evolution Perspective | 哈佛教授解密:睡眠、运动、糖和炎症7大误解-YyatTung

An Evolution Perspective | 哈佛教授解密:睡眠、运动、糖和炎症7大误解

歌手:YyatTung

时间:2024-12-02

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喔耶耶耶喔

Okay

So get ready for this

We're going way back in time like millions of years back

Oh Well

Yeah

We are if you want to underunderstand why momodern bodies just seem so prone to certain diseases well stick with us

Because we're going deep into human evolution

And this concept called mismatch diseases

Cool Yeah

We're using this super intriguing interview that hesent over with daniel leberman

Oh Yeah

Ah fasvard ard evolutionary biology

Yeah He's

He's great yeah

Um fascinating way to look at health through

Yeah

Ah evovotion ary lens right essentially our bodies are just incredibly well adapted yeah for a world that doesn't exist anymore have dated hardware running the latest software kind a sums it up

It's like we have all this evolution ary baggage we're carrying around yeah

Let's on packet

Yeah let on packet

But ah out yeah

Romanticizing the storage um no plio fantasies here exactly no pliofancies

It's about understand of the context for example leberman um 不有一有challenges

This very common perception that humans are inherently fragile right well i mean compared to like i don't know yeah a champ

We don't look so tough

We do not look so tough

But

But chaberman argues that while like yeah a champ might beat you

Yeah a wewaght lifting contest right

Humans are the undersputed champions of endorance

We can outrun pretty much anything

Yeah we cannot run as long distance ant we not distanmost anmpiuright persistence hunting wearing them down over miles and miles and miles

Excisely and this incredible standard

We have is really closely connected

Okay to our diet um we

We are

I'm divorce

Yeah

And we're incredibly adaptable yes and capable of thriving on this huge idea of oooothis

That's very amazing that our liver can handle all of that know know all different

Different things

But i mean

Does i make it harder

That's make healthy choices

Today i the incredidox of choice

I think that's great

I mean

I'm overwhelmed just thinking about all the options i have

When i go to the store

It's so true

Yeah

And this is interesting too because liberman debunks a common myth

Okay

About the human warortment to eat at meat

Oh Okay

We've eating ating at at at least two and half million years

Wow

And it played a crucial role in our evolution

Okay

And particularly in fueling those large brains

That we have so no more arguing that humans are natural arrivoors

Huh the evidence just doesn't support that okay

What i think is really fascinating is how leabor man connects things

Yeah

That you wouldn't think are connected like our external nose

Okay

To our ability to run long distances ces what our nose is designed for running

Tell me more i know right think about it the shape of our nose

Yeah

It's not just for looks

It's uh it's this marvel of engineering yeah

The natural humidifire

So the air enters the nnostles right

It travelles to this narrow passage

And then it expands into a larger space

Okay

So this creates turbulence

And that turbulence maximizes contact

Oh

So this creaas turmblance

Oh so it's like prewarming and moisoning the air we breathe exactly

And this is really important

It helps to recapture moisture as we exhail

Oh

If you ever noticed like uncold day how much less steam you see

When you breaout out your nose

Yeah

That's your nose doing its job

Uh it's amazing

And this this efficient system was just critical yeah for endance running yeit preprevented our ungs from drawing out that's so cool

I'm never going to look at my nose the same way again right it's more than just a place to hold it

My glasses and is amazing

Amazing and speaking of endurance yeah

Another kind of superpower that humans have sweating

Oh Yeah

I mean we are sweating machines

We are compared to a lot of other memmal

We traded our fur for this exceptional cooling system

But it's not necessarily hunting

Yeah

That drave its evolution leberman actually suggests

Yeah

It might have evohuneven yeso we were very good hunters okay so imagine our early ancestors yeah

The astrroopops right they're by pepeal

But they're not very fast

But t and ducks out there on the savana yeah

Like easy pray right yeah so liberon thetheorizis they adadapted forforging during the hottest part of the day

When the predators so weren't so active okay so sweating

Allow them to stay cool okay under this uh this cororchic sun so was was looking an early warning system

And don't need i'm too hot to hand me back off yeah

I'm too high so marmart suyeand this heafrgulation just beheeven more important

Right as we evolved uh skilled hunters okay

Chasing pray for mile yeah under african son

You need to serious

You need pull that yeah

You need a serious cooooling system okay

So we've got the running

The breathing sweating

But we can't get

Get the elephphant

The

The room

The big brain

Yeah

At a large brain

The large brain how does that fit into all of this

So the development of our big brains coinciook with this shift to hunting and gathering okay

你的这个it's a lifestyle that demandintellgence ence ooperperright and provided right much more yeah

Caloe dance food right cacost twenty percent of all of our energy

I know it's crazthose to our brains

It's crazy

It's a lot

It is

And where does a lot of that energy come from fat

Fat yeah

And fat is crucial right yeah

Fat is cvelopment reproduction energy storage yeah

Ah yeah

Labor man cautious that like most things in life yeah

It's about balance too much of a good thing

Right too much of a good thing like holiday cook is yes

Holiday cookis exactly

But so bad so lebrmman explains that yeah

Well fat is essential excess

Fat right leads to information right which is a key driver okay of many chronic diseases like diabetes and heart disease okay

And this is where it gets really interesting so okay

Our bodies evolved yeah to store fat for survival right

So when we die it

It triggers this primstarvation response

So that's why we crarave all the things

That we shouldn't be having

Thing

Thing

It's trying to avovoand

When we're trying to be good

Our bodies like nope

Our bodies like no

We need

We need sugar

We need the sugar

The carbs

Yeah It's

It's not just whilelpower it's biology

Biology um

Our bodies think we're in a faamine right

And they're craving those quick energy sources

Ah and then stress throws another ranrenin the woroh h everyone's favorite frirenomy um

I know so chronic stress elevates courtisl

Yeah

Our fighter flight hormone right

And guess what courort is all done

I don't know what does it do

It directs fat storage

Oh to the abdominal area that visceral at visueral fat yeah

The kind it's like not just a cosmetic concern

Exactly

Exactly visual fat is highly ly flammory right

So the ddererin incases the risks great of those chonic diseases okay

So we've got excess fat leading to information uh and then stress just throws gasoline on fire e the fire e this comcomplex terplay that contributes to what leberman calls mismatch diseases ok

So i think we need to define term like what are mismatch diseases

So they arise when our bodies right which are just beautifully adapted right for this completer either lifestyle collide with the reality of modern life of modern life

So i think heart disease diabetes

Yeah

Certain cancers okay

Even near sighdness conditions that were practically absent

Wow in preindustal al society

So heart disease which aa maor or kiler today yeah

It was basically nonexisted

Practically nonexist back ah that's crazy

It really underscores how much our environafaffects health th solute

And i guess unfortunately a lot of our modern comfort

Which know m seem benefical right

Actually contribute to these issues yeah

So give me an example of the price of comfort okay

So think about back pain okay

One of the most common

It's true complaints today yeah

And it's often a direct result of our

You know sedentary lifestyle

Our sedentary lifestyles yeah

Spenning hours hunch

Our desks over desks ks

I wonder how much time you spend sitting everyday

Oh

A lot me yeah

Too much way too much

Leberberman really stresses the importance of those movement breaks

Even if they're short yeah

They make a big difference okay

Interesting yeah

He found at the hadza okay

A modern hunter gathering group yeah

Sit for about ten hours a day

What just like us

They said as much as we do

But there's so active

I know so the key differences okay

They get up constantly all the time right tending fires chasing children yeah

Moving through other environment

They're not glue to their chairs right

So was not just how much is how tell we say the way we siyeah so more figeting okay

Let's slouching got it okay

And this is another one okay

The kind of seems counterintuitive okay

The hygie hypothesis okay way yeah

Our quest for cleanliness good backfire it's fascinated okay

By creating this hypersenatized yeah

World we might be disrupting yeah

The balance of our immune system

So our immune systems need a little dirt not dirt

But exposure to microbes right we've evolved alongside these microbes from millennia right learning to distinguish friend from foe okay

So by eliminating these microbes right we create this what leberman calls and unchallenged immmune stem okay

Which is more likely to overreact

So that's how we msubances like polin okay

And that's how we get ouergies

So it's like our immune system needs to be trained yeah

Like we train our bodies with exercise

Yeah

That's to create announcce

So that leads to this um crucial point

That liberman mamakes about yeah

We're so focused on treating the symptoms yeah

That we neglect

We neglect the root causes right he calls this cycle dissolution

Dissolution that sounds kind of scary

It's a powerful term

Yeah

It refers to this continuous cycle of treating the symptoms without addressing the root causes which allows the problem to just keep going to persist and even worse than overtime right to scary thought

But

But it's also kind of a all led acaction

Think think if know know this ah

Ah can change things

We can change things absolutely so what can we do

What can we do okay

So it might self familiar

But not just man advocates tes for ooay eating less process for otting titising movement getting up frequently yeah

If you have a desk job right and managing stress so basic stuff

Basic stuff

But now we know why

But now we know why

It's not just some saad diet

Yeah

Whatever it's like yeah

About lining our lives 's there our ancient body

The needs of our ancient body

I love that yeah

It makes me think he didn't really talk about cosmedics and personal care products

You didn't could those be contributing that's a great question to mismatch disease

That is a really great question

Yeah

Perurfect example yeah

Of how we can use this evolutionary lens

To think critically right about all these different aspects of our lives

And we slather on all stuff ff like we do yeah

And we don't really fully understand the long term effects

It makes me think about that whole dissolution idea again it does our are

We sacrificying our well being a good question

To look good

That's definitely a question

Worth pondering it is

It's a lot to think about it is

And i hope it makes you question yeah

What you consider to be normal

What is normal

And what choices you can make to have better health absolutely yeah

And while we're on the topic of things that can really impact our health yeah

We can't overlook the fascinating world yeah

Of our microbibiomoah

Yes

All those trillions of bacteria yeah

Liour mhoneus our own little cosystem

Your own personal ecosystem yeah

I remember that being a key point labor minte interview

Oh Yeah

It's

It's mine boggling

How much we're learning right about these microbes

Yeah

Crucial they are who are well being

And of course how are lifestyles yeah

Be disrupting them

Disrupting this ancient partnership

Ah well we've waged war on bacteria

I think for decades

We have with our anti bacterial soaps and hand senotizers

Yes

And well those definitely have have their place especially during a pandemic

Of course

Leabberman reminds us yeah

That we've evolved along aside these microbes for really long time

Yeah

They're not all villains right many of them are actually essential right for our health

He used that analogy we did about teenagers with nothing tial

Oh Yeah

Abboard immune system

Ah ah no real threat stifit right can turn on us

It's like our own internal security force yeah

Restless right and start seeing enemies everywhere exactly so by creating this overly sanentizzed right

We might be actually increasing our risk

Okay for think like allergigies yeah

It imimme diseases and even um mental health issues really the bacteria and our good yeah can affect how our brain works it's amazing

Wow

It really highlight ghinteinterconnected everything is it really doesn't makes me think yeah

Maybe we should rethink our relationship

I think so hyjane yeah

A little dirt we'll dirt isn't so bad

Not so bad

After all right

It's all about finding that balance

I guess it is like we've been talking about not too much too too little weather

We're talking about fat right exercise or bacteria

Exactly it's about um perpecting that ancient wisdom yeah of our bodies right and understanding how our modern choices really create this ripple effect yeah

And speaking of choices yeah

Yep ferman made a really interesting point about cultural evolution impacting our biology

He was talking about this idea of dissolution yeah

Dissolution yeah

And i think we mentioned it earlier we did

But it really stuck with me

It's a powerful concept

It is because it's almost like we're just letting these mismatch diseases just run wild yeah

Because we keep putting bandases on this symptom instead of addressing the root causes we

We ep tting sympmpm yeah

But the underlying problem remains it makes me think about our healthcare system

Oh Yeah

Often feels like it's more focused on treating the sick yeah

Than on preventing people

It's a very reactive system from getting sick rather than a proactive one ray

And as leberman suggests that as approach not not just costly ly it is

But it's also contributing to this mismatch diseases

Yes

So if we want to break free

Yes

This also cycle of dissolution

This elulubut we even begin will liberman en guguthat um um

Yeah

The first step is just knowledging the problem okay

We need to recognize

Yeah

That our modern environment right is often at byeyes with our evolved bodies

And that many of our lifestyle choices right contribute to these diseases

To these diseases

It's not about lalait's not about blame

It's about

It's about taking responsibility right

And it's not about abandoning modern life now altogether

Yeah I

I'm not ready to give up my smart phone neeither or indoor plummbing

I'm like indoor plumming right

Exactly it's not about going back to living in caase

It's about finding a balance

Balance exactly finding a balance between those conveniences of modern life yeah

And the need ds of our storage

Bodies of our storage bobodies okay

Understanding the trade off okay

So what are some practical things yeah

What can we do

We can do to bridge that gap

What liberman yeah is a huge proponent tive movement okay

没有没有

没有异议

We need to move yeah

Regularly yeah

In ways that challenge yeah

Our muscles on our bones okay

So walking okay

Running dancing lifting weights okay

It all counts he even said that regular physical activity can help prevent bone loss

It can

And i thought bone density was mostly determine by genetics in age

好的好的

Well those things do play a role right

But leberman exexplains that weight bearing exercise okay is crucial okay for building and maintaining strong bones

So even if your past yeah

Your peak bone building year

Yes yes

You can still slow down bone loss through exercise absolutely okay

That's incurtain

It's never too late to start right and exercise has this ripple effect yeah

It improve carcardivascular health hh boosts are moood sharpenons cognitive function yeah

And

And nal about about stress

Oh Yes

A natural mood lifter

It is

It's crucial for managing stress right

And we know that stress just breaks havoc reeks

Havoc c on our body elevates those courorses levevel contributes to fat storage information

So it really is all interconnected

Yes

It all comes back to that internenecveness yeah

It's a very holistic

It is you have held

Yes yes

Like all these different aspects of our lives

Yes it all woven together

Yes just what we eat right

It's not just how much we exercise

It's how much we exercise it's creating a lifestyle yeah

That supports are well being on all levels exactly and part of that yeah is questioning what we consider normal what ah down the al right we're stoto to we are the comforts of modern life

That we don't stop to think ooay ah suconsequence what the consuences be yeah

Ah the road

Road down the road

Yeah need to to be aare

I think so of these subtle ways

Yeah

Our environment is shaping us

Shaping us labor man even highlighted this um surprising link between our jaws

And how we eat yeah

So he's done research showing yeah

That the softness of modern processed foods yeah has actually led to well wow a decrease in jaw ze woal over generation so chewing on tougher jaws

It's like a work out

It could actually out our kids develop ed stronger jaws fascinate it is wow

And it just

It shows how even these seemingly insignificant changes in our environment

Right can have have these casadating effect

Skating effect on our biology

On our biology makes you wonder

What else is happy

That we're not even thinking about it's a humbling thought

It is

It is

And it just emphasize es important right obstained curious asking question right obcontinually learning about how to live yeah

A gging about ermany yeah with our evolved selves

It's like we need to become anthropologists you do of our own bodido i love that yeah

We need to study ourselves yeah

Undersociand our origins yes and make choices that honour our eevolutionary ass yes

But i mean it's not just about individual choices is it no

We also need to advocate for about societal level at socielelevel right crecreate vivironis is that court

That's support help yes and well being for everyone absolutely right

So we need to push for policies do that promote access to health food

Food forforful food

That encourage both llsal activity

Collectivity

And that reduce our exposure yes to harmful environmental factor

So to harmful environtal tal tor

Or it's mulltiprong it right

It requires indiindiduduresponsibility and and collective action direction

We need to change our habits we do

But we also need to change the systems

That are shaping our choices

Then shape our choices

And it's about recognizing yeah

That health is not just absence ence didiase

It's

It's ththving

It's about

About five

It's about living this all and bibrant ant yeyeah

Yeah our bibilogical and cultural heritage at the end of the interview yeah

Liberman man ft ft us this this thought provoking question

What would you be willing to die for today

Wow

And it really got me thinking

It makes you think about what truly matters it does

It forces us to confront our values yeah

Our priorities

Our sense of purpose right

What do we willing to fight for yeah

What do want legacy yedo

We want to leave hind ind quesquesabout questions

But it's think it can help us make sense

I think so too of those smaller yeah

Everyday choices absolutely right

It's about living in with intention yeah and appreciation yeah for this incredible gift of life

It's about pushing back

Pushing back against that dissolution

That dissolution

That dissolution has threening to diminish to diminih h our tential al potential a little healththy rebellion right like that's a good thing

Hehealthy rebels questioning the status qual

Yes

Challenging conventional wisdom

Yes

Forging ing own

Own paths yes towards a healther forgautheer and more fulfilling future yes and speaking of challenging conventional wisdom

Laborman didn't shy away from to get them the hieight in hypothesis

No did

Did this ideidea that exceve ve ananitation right

Acactually harming right it's immune system

It's definitely a topic that sparks debate it there's this delicate balance yeah to strike right

Between protecting ourselves from these harmful pathogen right allowing our immune systems to develop properly and then with the whole problem of 是有antibibitic tic resistance

Biotic resistance it gets even more complex

It does it's a huge problem

It's a serious threat to public hehealth

It

It really underscores the importance of using end of biotics wisely yeah

And explororyealternative tive right to treat infections

And this is where i think yeah

Liberman's evolutionary perpertive tive

Tive so valuable yeah

It encourages us to think long term yeah

It consequences of our actions yeah

And to look for solutions yeah

That are sustainable and aligned with our biological heritage yeah

We're part of you are web of life of complex

Web of life and our choices have ripple effects

Ripple effects that extend far beyond ourselves

And that brings me to another important yeah

Pect of all this yeah

The role of technology

Technology it's brought this incredible advancements in medicine

It has communication yeah

Countless other areas absolutely

But it's a double ge sort isn't it

It is it's a double ge sort

Yes

Technology is also create the world right

Where we're constantly bombarded with information right tethered to our devices yeah

Living increasingly sedenitary lives

So the things that we're designed to make our lives easier yeah

That making a ske

It's ironic isn't it

It is leberman makes a really good point

Okay that technology itself yeah

It's an inherently good or bad

Okay it's how we use it right

Right it matters

It's about finding that sweet spot

It's about finding that balance again right

Where technology serves us

Serves us not the other way around

Not the other way around right reclaiming our time

Reclaiming our time

Reclaiing our

Our tention

Rereclaiming our connect

Our connection to the natural world

So the natural world and recognizing yeah

That technology is going to keep

It's going to keep evolving

Volving and what maybe yep a mismatch

Today yep could be an advantage tomorrow right

So we need to stay adaptable we do

We need to stay adaptable right lexible yeah open to new ways of thinking right about our relationship of technology

We need to be active participants

Absolutely shaping the future of technology

Absolutely we need to stay informed yeah

Engage ask those tough questions yeah

And maybe maintained sense of humor about it

Oh Yeah

I remember leberth tying d the latest test

Alth trenyes of the latest health trends

Of the latest health trend and all the new products that come out

Yemabelieve the array and approach it with a critical eye

A critical eye right and not be afraid to laugh at the absurdity

Absurdity of some of things

Things of the claims

Out there

Just out there

Prepariculous yeah

Ah it's good not take ourourselves seriououly ly is yeah

Health th isn't just ah about following rules or being perperct ct

Being perperfect

About

About not ing connection yeah

Right momoment in movement connection

Connection nature

The simple pleasure of life

The simple pleasure

Yeah

It's about cultivating

It is a sense of wonder

Wonder curiosity

Gratitude

Gratitide de yeah

This gift ft being alive for this gift of being alive and maybe a little bit of mischif

Oh Yeah

Remember

When he said that um he did ds should be chewing on resonness gum

He did districicin their jaws

I loved that it's a playful approach

It's a serious topic

Absolutely

And it reminds me yeah

Health doesn't have to be doming gloom

Gum gloom

No

Right it can be fun

It can be

It can be adventurous

It can be adventuous

It can be rebellion

It can be rebellion

Yes

It's about reclalaiming our health

Our agency and conconnection to of a evolutionary

Evolutionary heritage

About embracing that full spectrum so full experict of a human experience so primal to the modern

And finding ways to integrate

To integrate them to support us integraving

Absolutely

And that's what i find so compelling me too about this whole mismatch depression

It's not about

It's not about vertaining a specific set of rules or behavior

It's about empowering us right with knowledge yeah understanding and just a deeper rereciation yefor this incredible plexity yeah and resilience are resence ence of human ation pleal

But it's about giving us the tool

It's just to make inform choices

Absolues with our values

A line with our value

Our goals

Our desire to live long healthy fulfilling lives

It's recognizing we're all

We're all in a journey on journey

And there's no one size fits all right approach to health and well being

It's finding what forks for us ah as individual yeah experiment

Experiexperiting ting adapt evolving as we go evolving

And it's about supporting each other

Supporting each other yeah along away way

Althe way sharing information

Sharing information resources encouragement as we navigate the challenge opportunities so after life of modern life and hopefully having a little fun

Along the way having a little fun

Friving a little fun

Laughter is good medicine

Laft is the best medicine

And reminds us yeah

We're not alone in this journey

We are not we're all in this together

In this together

And by working collaboratively yeah we can create a future

We're mismatch diseases are no longer the norm right

We can create a world

Yeah

Health vitality yes well being are accessible to all absolutely

And that's a future worth strumpting for it is

And it all starts at all staraawareness

Preurfililfuah a willingness and a willing ingfeland to that is quote

So let's keep learning

Keep questioning ep moving towards and a healthier

Healthier more fulfilling future

More fulfililfuture ture heselves ves for for ererilgenerations to come

Let's not forget yeah

Enjoy the ride

To enjoy the ride

Life is meant

It is to be lived experience saver

Saver yeah and yybe even little little it rough gh house a little rough housing

Just to keep our immune systems

To keep him on their toe

On their toe

Aa little healthy oe a little healthy

Co never heard anyone

Never heard anyone

And with that yeah will wrap up part too yethere of our deep dive into miss match diseases into mismatch diseases covered a lot of grap we have

But they're still so much more to explore so in part three

Part three

Yes

We're going to delve into some specific

Specific example

Examples of mismatch diseases

Okay will look at how they manifest their underlying causes raah potential strategies rate for preventional sttigation rait will also explore yeah this complex interplay of genetics

Environchoice

Ice listle choices in shaping aear't health outcomes 的对对

这这的这个

And will leave you with some some al al thoughts

Thoughts

Resources

Inspiration

Continue on your own yeah journey toward optable well being awesome so stay tune for part ar it

It well will continue this explplorand we will this fascinate

It's so fascinating and vital topic it is welcome back for the final part of our deep dive into mismatch diseases

It's been quite a journey so far

It has exploring the evolution ary routs of much burn health and all that yeah

But now i think it's time to kind of zoom in okay on some specific examples

Let's get down to the nadegreity

Let's get down to the needegreity

I like it so we've covered a lot of ground

Well you think about these broad concepts of mismatyeah

But think think it really hits home yeah

When you see how it actually manifest yeah

Real world in real life yeah

Affecting people every day exactly so let's start with a big one okay

Heart disease

Hard disease yeah

Liberman point it out

He did how rare

It was in pre industrial society

Right now it's a global al epidemic

Everywhere it

It is alalmost like our hearts are struggling to keep up yeah with modern life

They think they weren't built for this right yeah

It really highlights

How much our environment impact right are health

And you know there's a lot of play here

But you know the risk factors for heart disease

Yeah

Really do stem from these modern lifestyles right

So you think about diets

Higher process foods saturated fans added suggers all of that contributes to the build up of pack k right in our arteries

It's like we weren't design to handle all of that

Yeah

That constant influx of unhealthy food and our sedenitary lifestyle

Yes

Don't help

Don't help

Now just makes matters worse

Makes it worse

Yeah

It's maanother log on the fire and another log on the fire

I like that it all goes back to leberman's point about movement

It does we gotta move

Our bodies were made to move

Yes

It weren't meet to sit all ah right

And we can't forget about stress uh stress right

Those elevated cortisol levels that we talked about yeah

Contribute to information right and can 以even damage blood vessels okay

So that increases the risk of things like heart attacks and strokes

It's like this perfect storm of mismatch factoror it didididiet lack of exercise stress

Stress

It all comes together

Yeah

To create this major health crisis

It's not just heart disease

No

Not just heart disease

Diabetes is another big yeah

Another mismatch disease in closely link to diet and lifestyle yeah

I mean it's pretty alarming

It is how prevalent typed to diabetes has become especially

Especially in developed countries in the developed world

Yeah

So how exactly does dibecasfit in yeah

To this puzzle okay

To think about it okay

Our bodies evolved have to handle these occasional spikes and bloodchaer right like after eating fruor honey yor self exactly yeah

But our modern diets are just loaded with the refined sugars and processed carbon hydrry right

So our blood sugar

Sugar levels are just constantly yes

Like our systems are on overdrive all the time yes

All the time just trying to keep up with this

It's trying to keep up

I like that bombardment of sugar right

So that poor pankerous yeah

Which produces insulin to regulate blood sugar right it gets overoverwork othe time right the cells become resistant of sulin okay

And that's one type two diabetes

Tes velopps

And that insland resistance yeah

Linked to information it is right yeah

Which then just kind

Kind treinat it sets off this casadcascade of other health problem

A domomino effeah yeah

And again the lack of physical activity yes doesn't help it just compounds the issue yes makes ourselves even more more resistant

Resistant to insland yeah

So it's harder

So mumultifacacproblem it is yeah

But lack it's a complex web

How much we move

Yeah

Ah how n't manage our stress

It's a holistic problem

That requires a holistic solution

Yeah

It's not just about finding that magic pill

It's not no right it's about

It's about lifestyle changes

Making those lifestyle changes that are in line

And how we evolved working with

With bodiworking with our bodies yes not against them

Not against them

It's about advocating for those bigger changes

Absolutely right those societal changes

That are going to make those healthy choices

Yeah

And make it easier for everyone easier for everyone like

对

Improving access to fresh food yes

That's affordable creating more opportunities to move our bodies

Yes

Reducing our exposure to all these toxins in our environment

Yeah

Those are big changes

Thetheir systemic changes

But they're crucial

But they're necessary

Yes

Speaking of environmental factors yes

Let's talk about miopopa

Miopopa near nesisideness

Another example of a mismatch disease

Yeah

That's on the rise

Especially about

On kids

Especially on kids

Leberman mentioned that study

Ah Yeah

About the innuit population yeah

We're like the grandparents had perfect vision

Perfect vision

But then the grandchildren needed glasses

Needed glasses

That's a pretty start illustration

It is how quickly things can change

How amazing

How adadaptable

Our bodies are yeah

They did

But sometimes it works against us

So what's driving this increase in your sidenness well leabberman inthings

It's mostly do to our bodern visual environment right

So our eyes evolved yeah to focus on distant objejeright scanning the savana

Scanning the the saananscanning the savana looking

Looking for predator

But now now

Now 're just sting

Wehas been hours every day at screen staring it screen green books

Reading books

Our eyes have to adapt they do have adapt t ah and all these eclose up activities okay

Can actually change the shape of the eye

So even our eyes are showing signs

Can actually change an hours match it is wow

So how do we protect our kid's eyesight

Well

I mean is it just about limiting screen time

I mean that's definitely part of it okay

But leaver man emphasize es spending time outdoors

Geking kids to play outside

Where they can focus on things in the distance right can help prevent or slow down

Okay

My opia it's so simple

But it's so profound

Just getting back to nature

It's amazed

Just can prefit

There are health in so many ways

Yeah Okay

And this brings us back to the hygiene

Hypothesis

Yposis

We touched on it a little bit we did

But i think it's worth revisiting

It is because i'm still wrapping my head around yeah

It really challenges conventional thinking yeah

Clecleelliness

Ah this idea that are overly sanatized

Yeah might actually be contributing to the rise and allergies

How of immune diseases counter and too it

It isn't

It It is

It goes against everything

We've been taught about hygien

I know

But as leberman explained

Yeah

Our immune systems evolved in a world

That was teaming with microbes right

And some of them are bad

But many of them are good right

They actually helped to train our immune systems

Okay to know the difference right between good guys

Between good and bad

And the bad guys

They like book camp for immune system right

Exactly yeah

It's got a

They have to be exposed

Exposed

They have to be challenged the all these different things to build up that

That resilience yeah

Resilience yes

So when we try to limit all the germ right

We're actually depriving our immune stem of that training

Of that training yeah

And that disruption can then lead to an immune system yeah

That overreacts to thing

That's how you get allergies

That's how you allergies

Or even worse

Or even worse

Yeah attacking the body's own tissues yeah auto imimmune seseyeauto immundisease

So it's complex

It's complex

And there's a lot we don't know

We don't about this hygene hyypotheis right

But it definitely raises those questions

It raises a lot of questions about all that

That creating encleaniness especially with our kids right acwith with our kids not about like right throing out the basic hygienstah

But thout out wash hhand right washing our hand

But maybe we need to rethink our dependants on all those antibacteriproducts products

All that creating enenrionments that allow for some of that healthy expolothe

Healthy exporsure

That balance

That balance

And i feel like that idea of balance

It comes up again and again

Doesn't know it does it comes up with everything we're talking about yeah

Diet exercise

Stress management technology and right chnolology

It's about understanding that we're complex

We are our health is influenced by all these different thing

It's all interconnected yeah a holitic approves right polistic approach

And it's about empowering ourselves with knowledge

So we can form choices to support are well being yeah

So as we wrap up this deep dive yeah into match match diseyeah

What are some of the key take away for you for me

I think the biggest one is that our bodies yeah

Our incredible machines yeah

Shaped by millions of years of the evolution

The evolution they're adaptable

But we need to respect right are evolutionary heritage right

And make choices that support our biological need

And it's not just about individual responsibility right

Does not know right

It's also advocating for those sysystetic tic changes

Creating environment yeah

They make it easier are healthier

Tell you for everyone

Everyone like creating in a world

Where healthy choices are easy choices

Yes Right

Where fresh food is affordable and accessible

Yes

Where movements part of our daily live

Yes

And where we have support to manage stress

It's a big vision

It is a big vision

But it's a vision worth striving yeah

It is

And it requires us to keep learning yeah

Keep questioning

Ep questioning challenge the status quoo

Yeah

And look back to wisdom of our pass

Yes yes

And use that to inform the future

Right we owe to ourselves

We do to our kids to future generation to create a world

Where mismatch diseases with these diseases are not the norm yeah

They're not inevitable

It's a challenging mission it is

But it's also inspiring is

And it all begins withthat awareness

Aware that understanding with that willness to wilingness to embrace our evolutionary heritage

Our evolutionary here eryeah

So this deep dive hehas been eye mission it is

But we hope

We hope

So it's sparked your curivostion yeah

And inspired you to take action

To take action in your own life yeah

And remember you're not alone on this journey

You're not alone

There are a lot of resources out there

There are communities

People

People who are dedicated or dedicated to this

To this way of thinking about

Hey Yes

So keep exploring

Keep learning

Kemoving

Keep moving

Keep moving toward a healthier

Healthier and more fulfilling life

Yes

And don't forget to find fying life

Jojofind the fun and the process

Yes

Embrace your inner hunter gather get out there move your body connect with nature

Connect with nature saver the simple things in life

The simple things

And until next time

Yes

Keep questioning

Keep questioning

Keep challenging

Challenging

Keep striving for that future

Yes

We all thrive

Where we all thrive in harmony

In a harmony

With our bodies

With our environment

Yes

With each other

And

With each

Each And

And joining us

Thanks for

Joining us on this deep dive was see the next am

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